Naslov
Baclofen-induced dyshidrosiform bullous pemphigoid in a paraplegic patient complicated by methicillin- resistant staphylococcus aureus (MRSA) and urinary infection
(Baclofen-induced dyshidrosiform bullous pemphigoid in a paraplegic patient complicated by methicillin-resistant staphylococcus aureus (MRSA) and urinary infection)

Autori
Lugović-Mihić, Liborija ; Duvančić, Tomislav ; Pavić, Ivana ; Gverić-Grginić, Ana ; Šitum, Mirna ; Dediol, Iva

Izvornik
Acta dermatovenerologica Croatica (1330-027X) 27 (2019), 3; 184-187

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
bullous pemphigoid ; baclofen ; dyshidrosiform pemphigoid ; neurological disorder ; MRSA ; urinary infection ; complications

Sažetak
Bullous pemphigoid (BP) is an autoimmune disorder which is usually chronic, with blistering that predominantly affects the skin and occasionally the mucosa, and which includes several different types. One of them is a very rare dyshidrosiform type which is localized on the hands and feet with small or large blisters on the palmoplantar surfaces. BP resulting from a drug reaction is a relatively rare occurrence, and so far more than 50 different medications have been identified as triggers. The aim of this article was to present the case of a paraplegic patient who developed this rare dyshidrosiform type of BP while he was being neurologically treated with baclofen. In spite of therapy with systemic and topical corticosteroids and other measures, successful treatment was achieved only after eliminating baclofen from the patient’s regimen. His general state of health was seriously endangered due to nasal and skin methicillin-resistant Staphylococcus aureus (MRSA), urinary infection, and oral mycosis (soor), and he was at high risk of sepsis and a fatal outcome. Through our efforts, however, we managed to achieve an excellent outcome. According to our knowledge, this was the first case of baclofen-induced dyshidrosiform BP.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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