Naslov
Intra- and inter-operator reproducibility of automated cloud-based carotid lumen diameter ultrasound measurement

Autori
Saba, Luca ; Banchhor, Sumit K. ; Araki, Tadashi ; Višković, Klaudija ; Londhe, Narendra D. ; Laird, John R. ; Suri, Harman S. ; Suri, Jasjit S

Izvornik
Indian Heart Journal (0019-4832) 70 (2018), 5; 649-664

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Atherosclerosis ; Carotid ; Cloud-based ; Reliability ; Reproducibility

Sažetak
Background: Common carotid artery lumen diameter (LD) ultrasound measurement systems are either manual or semi-automated and lack reproducibility and variability studies. This pilot study presents an automated and cloud-based LD measurements software system (AtheroCloud) and evaluates its: (i) intra/inter-operator reproducibility and (ii) intra/inter-observer variability. Methods: 100 patients (83M, mean age: 68±11years), IRB approved, consisted of L/R CCA artery (200 ultrasound images), acquired using a 7.5-MHz linear transducer. The intra/inter-operator reproducibility was verified using three operator's readings. Near-wall and far carotid wall borders were manually traced by two observers for intra/inter-observer variability analysis. Results: The mean coefficient of correlation (CC) for intra- and inter-operator reproducibility between all the three automated reading pairs were: 0.99 (P<0.0001) and 0.97 (P<0.0001), respectively. The mean CC for intra- and inter- observer variability between both the manual reading pairs were 0.98 (P<0.0001) and 0.98 (P<0.0001), respectively. The Figure-of-Merit between the mean of the three automated readings against the four manuals were 98.32%, 99.50%, 98.94% and 98.49%, respectively. Conclusions: The AtheroCloud LD measurement system showed high intra/inter-operator reproducibility hence can be adapted for vascular screening mode or pharmaceutical clinical trial mode.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA