Naslov
Encefalitis uzrokovan West Nile virusom-radiološki nalazi s kliničkom korelacijom/West Nile encephalitis-radiologic findings with clinical correlation
(West Nile encephalitis-radiologic findings with clinical correlation)

Autori
Višković, Klaudija

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
PROGRAM I ZBORNIK SAŽETAKA / - , 2020, 28-28

Skup
SYMPOSIUM with International Participation: Zoonotic and vector-borne diseases in the "One Health" Context

Mjesto i datum
Zagreb, Hrvatska, 22.10.2020. - 23.10.2020

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
West Nile Virus ; Magnetic Resonance Diagnostics ; Neuroinvasive Disease

Sažetak
West Nile virus (WNV) meningoencephalitis and myelitis has become an emerging infection with rapid increases in the incidence and geographic range. The purpose of this presentation is to review the spectrum of magnetic resonance imaging (MRI) findings of the brain and spine in patients with documented WNV infection treated at the University Hospital for Infectious Diseases in Zagreb, Croatia and investigate a correlation between imaging findings and clinical presentation in the period between August and October 2018. MRI findings are reported as abnormal in about thirty percent of cases and generally are nonspecific. In our patients, MRI images in T2 and/or Fluis Attenuation Inversion recovery (FLAIR) sequences revealed hyperintensity signal lesions in deep brain structures, including the thalami, basal ganglia and cerebral peduncle. These lesions usually have no associated mass effect or abnormal contrast enhancement. One patient had confluent white matter lesion in periventricular region. We also report a patient with cauda equina arachnoiditis which is a rare manifestation of WNV neuroinvasive disease. MRI may also show the thickening and enhancement of leptomeninges. Diffusion Weighted Image (DWI) may detect an inflammation prior to signal intensity changes detected using T2/FLAIR. Differential diagnosis comprises demyelinating process in the brain including multiple sclerosis, acute disseminated encephalomyelitis, chronic microvascular white matter ischemic disease or other viral encephalitis. Differential diagnosis of findings in the spinal cord and cauda equina includes transverse myelitis, viral myelitis and leptomeningeal metastatic disease.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA