Pregled bibliografske jedinice broj: 1158821
Morphological Carotid Plaque Area Is Associated With Glomerular Filtration Rate: A Study of South Asian Indian Patients With Diabetes and Chronic Kidney Disease
Morphological Carotid Plaque Area Is Associated With Glomerular Filtration Rate: A Study of South Asian Indian Patients With Diabetes and Chronic Kidney Disease // Angiology, 71 (2020), 6; 520-535 doi:10.1177/0003319720910660 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 1158821 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Morphological Carotid Plaque Area Is Associated
With Glomerular Filtration Rate: A Study of South
Asian Indian Patients With Diabetes and Chronic
Kidney Disease
Autori
Puvvula, Anudeep ; Jamthikar, Ankush D. ; Gupta, Deep ; Khanna, Narendra N. ; Porcu, Michele ; Saba, Luca ; Viskovic, Klaudija ; Ajuluchukwu, Janet N. A. ; Gupta, Ajay ; Mavrogeni, Sophie ; Turk, Monika ; Laird, John R. ; Pareek, Gyan ; Miner, Martin ; Sfikakis, Petros P. ; Protogerou, Athanasios ; Kitas, George D. ; Nicolaides, Andrew ; Viswanathan, Vijay ; Suri, Jasjit S.
Izvornik
Angiology (0003-3197) 71
(2020), 6;
520-535
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
atherosclerosis ; cardiovascular disease ; carotid intima-media thickness ; chronic kidney disease ; estimated glomerular filtration rate ; morphological total plaque area ; risk assessment.
Sažetak
We evaluated the association between automatically measured carotid total plaque area (TPA) and the estimated glomerular filtration rate (eGFR), a biomarker of chronic kidney disease (CKD). Automated average carotid intima-media thickness (cIMTave) and TPA measurements in carotid ultrasound (CUS) were performed using AtheroEdge (AtheroPoint). Pearson correlation coefficient (CC) was then computed between the TPA and eGFR for (1) males versus females, (2) diabetic versus nondiabetic patients, and (3) between the left and right carotid artery. Overall, 339 South Asian Indian patients with either type 2 diabetes mellitus (T2DM) or CKD, or hypertension (stage 1 or stage 2) were retrospectively analyzed by acquiring cIMTave and TPA measurements of their left and right common carotid arteries (CCA ; total CUS: 678, mean age: 54.2 ± 9.8 years ; 75.2% males ; 93.5% with T2DM). The CC between TPA and eGFR for different scenarios were (1) for males and females -0.25 (P < .001) and -0.35 (P < .001), respectively ; (2) for T2DM and non-T2DM -0.26 (P < .001) and -0.49 (P = .02), respectively, and (3) for left and right CCA -0.25 (P < .001) and -0.23 (P < .001), respectively. Automated TPA is an equally reliable biomarker compared with cIMTave for patients with CKD (with or without T2DM) with subclinical atherosclerosis.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Klinika za infektivne bolesti "Dr Fran Mihaljević",
Zdravstveno veleučilište, Zagreb,
Fakultet zdravstvenih studija u Rijeci
Profili:
Klaudija Višković
(autor)