Naslov
Treatment of intrabony defects with a combination of hyaluronic acid and deproteinized porcine bone mineral

Autori
Božić, Darko ; Ćatović, Ivan ; Badovinac, Ana ; Musić, Larisa ; Par, Matej ; Sculean, Anton

Izvornik
Materials (1996-1944) 14 (2021), 22; 6795, 12

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
hyaluronic acid ; periodontal regeneration ; intrabony defects ; microsurgery ; periodontitis ; surgical flaps

Sažetak
This study evaluates the clinical outcomes of a novel approach in treating deep intrabony defects utilizing papilla preservation techniques with a combination of hyaluronic acid (HA) and deproteinized porcine bone mineral. 23 patients with 27 intrabony defects were treated with a combination of HA and deproteinized porcine bone mineral. Clinical attachment level (CAL), pocket probing depth (PPD), gingival recession (REC) were recorded at baseline and 6 months after the surgery. Results: At 6 months, there was a significant CAL gain of 3.65 ± 1.67 mm (p < 0.001) with a PPD reduction of 4.54 ± 1.65 mm (p < 0.001), which was associated with an increase in gingival recession (0.89 ± 0.59 mm, p < 0.001). The percentage of pocket resolution based on a PPD ≤4 mm was 92.6% and the failure rate based on a PPD of 5 mm was 7.4%. The present findings indicate that applying a combined HA and xenograft approach in deep intrabony defects provides clinically relevant CAL gains and PPD reductions compared to baseline values and is a valid new approach in treating intrabony defects.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina

POVEZANOST RADA