Pregled bibliografske jedinice broj: 1155108
Protein induced lipid demixing in homogeneous membranes
Protein induced lipid demixing in homogeneous membranes // Physical Review Research, 3 (2021), 4; L042013-1 doi:10.1103/physrevresearch.3.l042013 (međunarodna recenzija, pismo, znanstveni)
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Naslov
Protein induced lipid demixing in homogeneous membranes
Autori
Stumpf, Bernd Henning ; Nowakowski, Piotr ; Eggeling, Christian ; Maciołek, Anna ; Smith, Ana-Sunčana
Izvornik
Physical Review Research (2643-1564) 3
(2021), 4;
L042013-1
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo, znanstveni
Ključne riječi
homogeneous membranes
Sažetak
Specific lipid environments are necessary for the establishment of protein signaling platforms in membranes, yet their origin has been highly debated. We present a continuum, exactly solvable model of protein induced local demixing of lipid membranes. The coupling between a local composition and a local thickness of the membrane induces lipid domains around inclusions with hydrophobic mismatch, even for temperatures above the miscibility critical point of the membrane. The model qualitatively explains the experimentally observed formation of lipid domains induced by anchoring of reconstituted actin in flat supported lipid bilayers.
Izvorni jezik
Engleski
Znanstvena područja
Fizika
Poveznice na cjeloviti tekst rada:
Pristup cjelovitom tekstu rada doi journals.aps.org journals.aps.org puls.physik.fau.deCitiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Emerging Sources Citation Index (ESCI)
