Naslov
PARAMETERS OF IRON METABOLISM IN ACUTELY DECOMPENSATED HEART FAILURE PATIENTS

Autori
Marušić, Filip

Vrsta, podvrsta i kategorija rada
Ocjenski radovi, diplomski rad, diplomski

Fakultet
Medicinski fakultet

Mjesto
Split

Datum
12.07

Godina
2019

Stranica
49

Mentor
Božić, Joško

Ključne riječi
Heart Failure, Anemia Iron-Deficiency

Sažetak
Objectives: The aim of the study was to compare how many patients with acute decompensated heart failure have iron deficiency or anemia and laboratory data between patients with acute decompensated heart failure when divided in groups based on iron and anemic status. Material and methods: This was a clinical, cross-sectional study, conducted between January 2018 and January 2019, that included a total of 60 consecutive patients with acute decompensation of chronic heart failure at Department of Cardiology of the University Hospital of Split. Upon patient’s arrival to hospital systolic and diastolic blood pressure was measured. Venous blood sampling was performed within 24 hours of admission. Chemiluminescent Microparticle Immunoassay was used for quantitative determination of ferritin. For serum iron spectrophotometry with ferrous chromogen was used. Complete blood count was determined using standard flow-cytometry-based hematologic analysis. Results: In this study the majority of patients had anemia and/or iron deficiency. Anemia without iron deficiency (22% of sample or 59% of anemic patients) was more prevalent than anemia with iron deficiency (15% of total population or 41% of anemic patients). There was significant difference in DBP between the groups with the lowest DBP observed in patients with anemia and iron deficiency (P=0.010). In patients with acute decompensated heart failure and anemia or iron deficiency higher levels of urea (P=0.031) and creatinine (P=0.020) were observed than in other subgroups. There was no significant difference in biochemical tests between groups. Conclusion: A significant number of patients hospitalized due to acute decompensated heart failure have anemia and/or iron deficiency. Diastolic blood pressure was lowest in patients with anemia and iron deficiency compared to other groups. Further research is necessary to draw any conclusions

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA