Naslov
Malnutrition-inflammation score and quality of life in hemodialysis patients

Autori
Tadic, Djordje

Vrsta, podvrsta i kategorija rada
Ocjenski radovi, diplomski rad, diplomski

Fakultet
Medicinski fakultet

Mjesto
Split

Datum
12.07

Godina
2019

Stranica
49

Mentor
Božić, Joško

Ključne riječi
Renal Insufficiency Chronic, Renal Dialysis, Quality of Life

Sažetak
Objectives: Living on hemodialysis is a challenge to many patients, impacting various aspects of their lives and ultimately influencing their quality of life. The aim of this was to determine the differences in quality of life between male and female patients on hemodialysis and to evaluate the relationship between quality of life and malnutrition-inflammation score. Patients and methods: This study included 50 patients in total, 26 males and 24 females. To evaluate health related quality of life the Short Form-36 questionnaire was utilized. This is a multifunctional, non-disease specific 36 question health survey in 8 different domains. In addition to this, the malnutrition-inflammation score (MIS) which included four sections (nutritional history, physical examination, body mass index, and laboratory values) was determined. Results: Females had statistically significantly lower scores than males in the following domains: physical functioning (48.7±35.0 vs. 68.4±26.9 ; P=0.029), energy/vitality (70.4±20.1 vs. 84.6±12.0 ; P=0.004), emotional well-being (71.8±18.1 vs. 83.5±10.1 ; P=0.008), pain (75.5±36.8 vs. 95.7±14.2 ; P=0.005) and general health perception (37.1±10.4 vs. 44.6±14.9 ; P=0.042). Older age was associated with lower quality of life in 4 of the questionnaire domains: physical functioning (r= -0.334 ; P=0.017), role limitations both physical (r= -0.298 ; P=0.035) and emotional (r= -0.361 ; P=0.010) and social functioning (r= -0.309 ; P=0.029). Moreover, the duration of the chronic kidney disease only negatively influenced the domain of general health perception (r= -0.283 ; P=0.047). The amount of time on dialysis negatively affected the domains of energy/vitality (r= -0.326 ; P=0.020) and emotional well-being (r= -0.282 ; P=0.047). Additionally, there was statistically significant negative correlation between MIS and all domains of SF-36 questionnaire. Conclusion: We can conclude that female patients on dialysis had lower health related quality of life when compared to men. Furthermore, quality of life inversely correlated with malnutrition-inflammation status.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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