Naslov
Effect of inbreeding and endogamy on occlusal traits in human isolates

Autori
Lauc, Tomislav ; Rudan, Igor ; Campbell, Harry ; Rudan, Pavao

Izvornik
Journal of Orthodontics (1465-3125) 30 (2003); 301-308

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
inbreeding ; endogamy ; occlusal traits ; human isolates

Sažetak
The aim of this study was to discuss the genetic basis of occlusal traits through analysing the effects of inbreeding in a subdivided isolated community. The sample comprised 224 dental casts of children aged 6 to 15 years from 15 villages of the Island of Hvar, Croatia. Studied traits were Angle class, degree of progression, overjet, vertical bite, overbite and intraarch relations. Two different designs were applied: (a) Children with complete grandparental endogamy (all four grandparents born in the village of residence of the examinee) were compared to the children with incomplete grandparental endogamy across all studied villages. (b) Children resident in the group of villages with high prevalence of inbreeding were compared to children resident in the groups of villages with moderate and low prevalence of inbreeding. In both designs inbreeding seemed to increase the mean values of overjet, overbite and vertical bite, while it had little or no effect on intraarch relations. Angle classes and degree of progression were correlated to inbreeding at the individual level, but this was not supported at the population level. The study implies that there are differences in importance of heredity among different occlusal traits and that their genetic basis is probably highly polygenic and in considerable part influenced by recessive genetic variants.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita, Etnologija i antropologija

POVEZANOST RADA