Naslov
Introducing the slope of the oxygen desaturation curve as a novel index in assessing phenotypes in severe OSA patients

Autori
Demirovic, Sijana ; Lusic Kalcina, Linda ; Pavlinac Dodig, Ivana ; Pecotic, Renata ; Valic, Maja ; Dogas, Zoran

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
7th Croatian Neuroscience Congress / - Zadar, 2019, 102-102

Skup
7th Croatian Neuroscience Congress

Mjesto i datum
Zadar, Hrvatska, 12.09.2019. - 15.09.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Recenziran

Ključne riječi
OSA ; sleep ; ODI ; saturation

Sažetak
The aim of this study was to investigate the relationships between SI and AHI with daytime sleepiness, sleep efficiency and comorbidity presence in severe OSA patients. A total of 111 patients who underwent whole-night polysomnography (PSG) at the Split Sleep Medicine Centre with severe OSA (AHI≥30) were included. Among PSG parameters AHI and sleep efficiency were analyzed. Daytime sleepiness was assessed by Epworth Sleepiness Scale (ESS). Arterial hypertension, diabetes mellitus type 2 (DM2) and depression were self-reported. The SI was calculated as the averaged quotient of the difference between the blood oxygen saturation before and after the obstructive apnea episode and the duration of the episode throughout the night. Both indices, SI and AHI, predicted daytime sleepiness in severe OSA patients without comorbidities. SI better predicted sleep efficiency in severe OSA patients with hypertension, as well as in the patients without depression. The slope of the oxygen desaturation curve index, as a novel OSA severity index, could help in understanding the impact of hypoxia in different OSA phenotypes.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

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