Pregled bibliografske jedinice broj: 1152210
New lectin ligands: Testing of Amadori rearrangement products with a series of mannoside-specific lectins
New lectin ligands: Testing of Amadori rearrangement products with a series of mannoside-specific lectins // Carbohydrate Research, 475 (2019), 65-68 doi:10.1016/j.carres.2019.01.010 (međunarodna recenzija, članak, ostalo)
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Naslov
New lectin ligands: Testing of Amadori rearrangement
products with a series of mannoside-specific lectins
Autori
Prasch, Herwig ; Hojnik, Cornelia ; Lindhorst, Thisbe K. ; Didak, Blanka ; Landemarre, Ludovic ; Wrodnigg, Tanja M.
Izvornik
Carbohydrate Research (0008-6215) 475
(2019);
65-68
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo
Ključne riječi
Carbohydrate-lectin interactionsAmadori rearrangementC-Glycosyl-type glycoconjugatesAntiadhesivesInhibition assay
Sažetak
1-(N-Phenyl)amino-1-deoxy-α-D-manno-hept-2-ulose (2) and two multivalent BSA-based structures 7 and 8, d-manno-configured C-glycosyl-type compounds derived from an Amadori rearrangement, were evaluated as ligands for mannoside-specific lectins of various sources. The determination of the concentration corresponding to 50% of inhibition (IC50) is described. Multivalency turned out to effectively influence ligand selectivity and lectin binding.
Izvorni jezik
Engleski
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE