Pregled bibliografske jedinice broj: 1149451
A brief overview of BNIP3L/NIX receptor-mediated mitophagy
A brief overview of BNIP3L/NIX receptor-mediated mitophagy // FEBS Open Bio, 11 (2021), 12; 3230-3236 doi:10.1002/2211-5463.13307 (međunarodna recenzija, članak, znanstveni)
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Naslov
A brief overview of BNIP3L/NIX receptor-mediated
mitophagy
Autori
Marinković, Mija ; Novak, Ivana
Izvornik
FEBS Open Bio (2211-5463) 11
(2021), 12;
3230-3236
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
BNIP3L/NIX ; mitochondria ; mitophagy ; reticulocytes
Sažetak
Mitophagy is a form of autophagy specialized to selectively remove mitochondria. Although the PINK1/Parkin pathway is the best described mitophagy of damaged mitochondria, receptor/mediated mitophagy seems to have a pivotal role in cellular development and specialization. The most studied mitophagy receptor BNIP3L/NIX is shown to be important for the programmed removal of healthy mitochondria during terminal differentiation of erythrocytes, but its role has been proven in various cell types. Despite recent advances in our understanding of its regulation by phosphorylation and dimerization, there remain numerous questions on how BNIP3L/NIX tightly balances between cellular life and death decisions. This brief review intends to summarize ongoing dilemmas related to BNIP3L/NIX.
Izvorni jezik
Engleski
Znanstvena područja
Biologija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)
POVEZANOST RADA
Projekti:
HRZZ-UIP-2013-11-5246 - Uloga receptora autofagije u selektivnom uklanjanju mitohondrija (AutoMito) (Novak Nakir, Ivana, HRZZ ) ( CroRIS)
Ustanove:
Medicinski fakultet, Split
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
