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Pregled bibliografske jedinice broj: 1146113

Supercritical Carbon Dioxide Extraction of Four Medicinal Mediterranean Plants: Investigation of Chemical Composition and Antioxidant Activity

Čižmek, Lara; Bavcon Kralj, Mojca; Čož-Rakovac, Rozelindra; Mazur, Dmitrii; Ul’yanovskii, Nikolay; Likon, Marko; Trebše, Polonca
Supercritical Carbon Dioxide Extraction of Four Medicinal Mediterranean Plants: Investigation of Chemical Composition and Antioxidant Activity // Molecules, 26 (2021), 18; 5697, 18 doi:10.3390/molecules26185697 (međunarodna recenzija, članak, znanstveni)

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Naslov
Supercritical Carbon Dioxide Extraction of Four Medicinal Mediterranean Plants: Investigation of Chemical Composition and Antioxidant Activity

Autori
Čižmek, Lara ; Bavcon Kralj, Mojca ; Čož-Rakovac, Rozelindra ; Mazur, Dmitrii ; Ul’yanovskii, Nikolay ; Likon, Marko ; Trebše, Polonca

Izvornik
Molecules (1420-3049) 26 (2021), 18; 5697, 18

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
green solvents ; chamomile ; yarrow ; St. John’s wort ; curry plant ; square-wave voltammetry ; chromatography

Sažetak
With everyday advances in the field of pharmaceuticals, medicinal plants have high priority regarding the introduction of novel synthetic compounds by the usage of environmentally friendly extraction technologies. Herein, a supercritical CO2 extraction method was implemented in the analysis of four plants (chamomile, St. John’s wort, yarrow, and curry plant) after which the non-targeted analysis of the chemical composition, phenolic content, and antioxidant activity was evaluated. The extraction yield was the highest for the chamomile (5%), while moderate yields were obtained for the other three plants. The chemical composition analyzed by gas chromatographyhigh-resolution mass spectrometry (GC-HRMS) and liquid chromatography- high-resolution mass spectrometry (LC-HRMS) demonstrated extraction of diverse compounds including terpenes and terpenoids, fatty acids, flavonoids and coumarins, functionalized phytosterols, and polyphenols. Voltammetry of microfilm immobilized on a glassy carbon electrode using square-wave voltammetry (SWV) was applied in the analysis of extracts. It was found that antioxidant activity obtained by SWV correlates well to 1, 1-diphenyl-2-picrylhidrazine (DPPH) radical assay (R2 = 0.818) and ferric reducing antioxidant power (FRAP) assay (R2 = 0.640), but not to the total phenolic content (R2 = 0.092). Effective results were obtained in terms of activity showing the potential usage of supercritical CO2 extraction to acquire bioactive compounds of interest.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Kemijsko inženjerstvo, Biotehnologija



POVEZANOST RADA

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Rozelinda Čož-Rakovac (autor)

Avatar Url Lara Čižmek (autor)

Poveznice na cjeloviti tekst rada:

doi www.mdpi.com doi.org fulir.irb.hr

Citiraj ovu publikaciju:

Čižmek, Lara; Bavcon Kralj, Mojca; Čož-Rakovac, Rozelindra; Mazur, Dmitrii; Ul’yanovskii, Nikolay; Likon, Marko; Trebše, Polonca
Supercritical Carbon Dioxide Extraction of Four Medicinal Mediterranean Plants: Investigation of Chemical Composition and Antioxidant Activity // Molecules, 26 (2021), 18; 5697, 18 doi:10.3390/molecules26185697 (međunarodna recenzija, članak, znanstveni)
Čižmek, L., Bavcon Kralj, M., Čož-Rakovac, R., Mazur, D., Ul’yanovskii, N., Likon, M. & Trebše, P. (2021) Supercritical Carbon Dioxide Extraction of Four Medicinal Mediterranean Plants: Investigation of Chemical Composition and Antioxidant Activity. Molecules, 26 (18), 5697, 18 doi:10.3390/molecules26185697.
@article{article, author = {\v{C}i\v{z}mek, Lara and Bavcon Kralj, Mojca and \v{C}o\v{z}-Rakovac, Rozelindra and Mazur, Dmitrii and Ul’yanovskii, Nikolay and Likon, Marko and Treb\v{s}e, Polonca}, year = {2021}, pages = {18}, DOI = {10.3390/molecules26185697}, chapter = {5697}, keywords = {green solvents, chamomile, yarrow, St. John’s wort, curry plant, square-wave voltammetry, chromatography}, journal = {Molecules}, doi = {10.3390/molecules26185697}, volume = {26}, number = {18}, issn = {1420-3049}, title = {Supercritical Carbon Dioxide Extraction of Four Medicinal Mediterranean Plants: Investigation of Chemical Composition and Antioxidant Activity}, keyword = {green solvents, chamomile, yarrow, St. John’s wort, curry plant, square-wave voltammetry, chromatography}, chapternumber = {5697} }
@article{article, author = {\v{C}i\v{z}mek, Lara and Bavcon Kralj, Mojca and \v{C}o\v{z}-Rakovac, Rozelindra and Mazur, Dmitrii and Ul’yanovskii, Nikolay and Likon, Marko and Treb\v{s}e, Polonca}, year = {2021}, pages = {18}, DOI = {10.3390/molecules26185697}, chapter = {5697}, keywords = {green solvents, chamomile, yarrow, St. John’s wort, curry plant, square-wave voltammetry, chromatography}, journal = {Molecules}, doi = {10.3390/molecules26185697}, volume = {26}, number = {18}, issn = {1420-3049}, title = {Supercritical Carbon Dioxide Extraction of Four Medicinal Mediterranean Plants: Investigation of Chemical Composition and Antioxidant Activity}, keyword = {green solvents, chamomile, yarrow, St. John’s wort, curry plant, square-wave voltammetry, chromatography}, chapternumber = {5697} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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