Naslov
Clinical application of the RONNA G4 system – preliminary validation of 23 robotic frameless brain biopsies

Autori
Dlaka, Domagoj ; Švaco, Marko ; Chudy, Darko ; Jerbić, Bojan ; Šekoranja, Bojan ; Šuligoj, Filip ; Vidaković, Josip ; Almahariq, Fadi ; Romić, Dominik ; Raguž, Marina

Izvornik
Croatian medical journal (0353-9504) 62 (2021), 4; 318-327

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
RONNA G4 ; neuronavigation ; robotics ; neurosurgery

Sažetak
Aims: To report the outcomes of robot-assisted brain biopsies performed using a novel RONNA G4 system. The system was developed by a research group from the Faculty of Mechanical Engineering and Naval Architecture and a team of neurosurgeons from Dubrava University Hospital, University of Zagreb School of Medicine. Methods: This prospective study included 49 biopsies analyzed during one year: 23 robotic frameless and 26 frame-based Leksell stereotactic biopsies. We analyzed the presenting symptoms, tumor range and location, postoperative complications, pathohistological diagnosis, diagnostic yield, as well as operation and hospitalization duration. The target point error was calculated to assess the accuracy of the RONNA system. Results: No postoperative mortality, morbidity, or infections were observed. In the frameless robotic biopsy group, only one pathohistological diagnosis was inconclusive. Therefore, the diagnostic yield was 95.6% (22/23), similar to that of the framebased Leksell stereotactic biopsy group (95.1% or 25/26). The average target point error in the frameless robotic biopsy group was 2.15±1.22 mm (range 0.39-5.85). Conclusion: The RONNA G4 robotic system is a safe and accurate tool for brain biopsy, although further research warrants a larger patient sample, comparison with other robotic systems, and a systematic analysis of the entry and target point errors.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne tehničke znanosti, Kliničke medicinske znanosti

POVEZANOST RADA