Naslov
Carbon dioxide supercritical fluid extracts from yarrow and rose hip herbal dust as valuable source of aromatic and lipophilic compounds

Autori
Vidović, Senka ; Vasić, Ana ; Vladić, Jelena ; Jokić, Stela ; Aladić, Krunoslav ; Gavarić, Aleksandra ; Nastić, Nataša

Izvornik
Sustainable chemistry and pharmacy (2352-5541) 22 (2021); 100494, 16

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
herbal dust ; supercritical carbon dioxide extraction ; gas chromatography ; bioactive compounds

Sažetak
The present study was designed to demonstrate the potential of supercritical extracts from Achillea millefolium and Rosa canina herbal dust, and their mixtures, as a source of valuable aromatic and lipophilic compounds. The supercritical carbon dioxide extraction (SFE- CO2) was performed at the pressures from 10-30 MPa, providing the total extraction yields (EY) in the range from 0.12 to 10.57%, being the highest when pure R. canina herbal dust was extracted using SFE-CO2 at 30 MPa for 5 h. Chemical profiles of SFE-CO2 extracts were determined by GC-MS and GC- FID. Oxygenated monoterpenes and sesquiterpene hydrocarbons were among the most abundant compounds in the extracts produced from A. millefolium and mixtures with a higher share of A. millefolium herbal dust. In the same mixtures, at the pressure of 10 MPa, a cosolvent effect was observed, which provided enhanced extraction of eucalyptol. The major tocol in A. millefolium and R. canina mixtures was α-tocopherol (589.49 mg/L). By investigating the influence of extraction pressure, it has been determined that higher compound recoveries could be obtained at lower pressures. The results clearly demonstrate that SFE-CO2 extracts of the A. millefolium and R. canina and their herbal dust mixtures are a promising source of valuable compounds to be used in pharmaceutical formulations.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija

POVEZANOST RADA