Naslov
Synthesis and stereoselective catalytic transformations of 3-hydroxyisoindolinones

Autori
Topolovčan, Nikola ; Gredičak, Matija

Izvornik
Organic & biomolecular chemistry (1477-0520) 19 (2021); 4637-4651

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
3-hydroxyisoindolinones

Sažetak
This review focuses on the synthesis of 3- hydroxyisoindolinones, and their application as substrates in stereoselective catalytic transformations reported from 2010 to date. These compounds have attracted much attention among synthetic chemists, as they are integral structural parts of a number of natural products and biologically active compounds. The first part of this review covers methods based on electrochemical, photochemical, and thermal reactions for the synthesis of 3- hydroxyisoindolinones. The second part focuses on their employment as substrates in transition metal-catalyzed and organocatalyzed stereoselective transformations for the preparation of chiral 3-substituted isoindolinone derivatives.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA