Naslov
Bone repair of the rat calvarial defect after application of the xenogeneic biomaterials and dentin

Autori
Jerbić Radetić, Ana Terezija ; Perić Kačarević, Željka ; Zoričić Cvek, Sanja ; Erjavec, Igor ; Omrčen, Hrvoje ; Cvijanović Peloza, Olga

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Bone reports, 14 (2021), Suppl / - , 2021, 4-4

Skup
48th European Calcified Tissue Society Congress (ECTS 2021)

Mjesto i datum
Online, 06.05.2021. - 08.05.2021

Vrsta sudjelovanja
Ostalo

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
xenograft ; autograft ; autologous dentin

Sažetak
Background/Introduction: Nowdays in oral implantology, natural biomaterials are available, which can be autograft and xenograft. Autologous dentin has been increasingly used in the process of alveolar preservation. Autologous dentin in GBR comes as a natural choice considering that it has the most similar composition of organic and inorganic substances with bone tissue. The presence of BMPs in dentin indicates its pronounced osteoinductive properties. Rapidly absorbable biomaterial can disappear before osteoconduction of osteogenic cells and generate new bone formation, whilst, non-resorbable biomaterials, prevent primary osteogenesis. There is a tendency to use new biomaterials based on magnesium alloy. The reason is that magnesium is biodegradable and it is expected that the biomaterial enriched with magnesium alloy could be completely degraded. Purpose: The aim was to compare 3D parameters of the bone specimens after application of a new xenogeneic biomaterial (Cerabone with magnesium) with the devitalized dentin, Cerabone and Cerabone with autologous bone. Methods: After calvarial bone tissue specimen was obtained at days 7, 15 and 30, micro- CT device (Skyscan 1076 micro-CT high resolution in vivo scanner) was used to obtain 3D parameter values: BV/TV (%), Tb.Th (mm), Tb.N (1/mm), Tb.Sp (mm). Results: The results of the bone volume BV/TV (%) are presented at the figure 1. Overall BV/TV score, no matter which biomaterial was implanted, revealed the highest value at day 15 (53, 19 %), which was statistically significant compared to days 7 (27, 7 %) and 30 (36, 77%), p<0.01.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA