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Pregled bibliografske jedinice broj: 1127653

Structural, antioxidant, antiproliferative, and in-silico study of pyridine-based hydrazonyl- selenazoles and their sulphur isosteres

Araškov, Jovana; Nikolić, Milan; Armaković, Stevan; Rodić, Marko; Višnjevac, Aleksandar; Padron, Jose; Todorović, Tamara; Filipović, Nenad
Structural, antioxidant, antiproliferative, and in-silico study of pyridine-based hydrazonyl- selenazoles and their sulphur isosteres // Journal of molecular structure, 1240 (2021), 130512, 13 doi:10.1016/j.molstruc.2021.130512 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1127653 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Structural, antioxidant, antiproliferative, and in-silico study of pyridine-based hydrazonyl- selenazoles and their sulphur isosteres

Autori
Araškov, Jovana ; Nikolić, Milan ; Armaković, Stevan ; Rodić, Marko ; Višnjevac, Aleksandar ; Padron, Jose ; Todorović, Tamara ; Filipović, Nenad

Izvornik
Journal of molecular structure (0022-2860) 1240 (2021); 130512, 13

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Hydrazonyl–thiazoles ; Single crystal X-ray analysis ; Antiproliferative activity ; Antioxidant activity ; Drug likeness parameters ; DFT

Sažetak
To evaluate the impact of chalcogen atom type, we performed a comparative study of antioxidant capacity and antiproliferative activity of a focused library of three pyridine-based hydrazonyl-1, 3-selenazoles and their sulfur isosteres in five antioxidant assays and in six human solid tumor cell lines, respectively. Insilico calculations were further used to check pharmacokinetic profiles of investigated compounds such as drug-likeness parameters and interaction with water. Generally, selenium compounds appear to be more potent in comparison to sulfur isosteres in the performed essays.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)



POVEZANOST RADA

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Aleksandar Višnjevac (autor)

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com doi.org

Citiraj ovu publikaciju:

Araškov, Jovana; Nikolić, Milan; Armaković, Stevan; Rodić, Marko; Višnjevac, Aleksandar; Padron, Jose; Todorović, Tamara; Filipović, Nenad
Structural, antioxidant, antiproliferative, and in-silico study of pyridine-based hydrazonyl- selenazoles and their sulphur isosteres // Journal of molecular structure, 1240 (2021), 130512, 13 doi:10.1016/j.molstruc.2021.130512 (međunarodna recenzija, članak, znanstveni)
Araškov, J., Nikolić, M., Armaković, S., Rodić, M., Višnjevac, A., Padron, J., Todorović, T. & Filipović, N. (2021) Structural, antioxidant, antiproliferative, and in-silico study of pyridine-based hydrazonyl- selenazoles and their sulphur isosteres. Journal of molecular structure, 1240, 130512, 13 doi:10.1016/j.molstruc.2021.130512.
@article{article, author = {Ara\v{s}kov, Jovana and Nikoli\'{c}, Milan and Armakovi\'{c}, Stevan and Rodi\'{c}, Marko and Vi\v{s}njevac, Aleksandar and Padron, Jose and Todorovi\'{c}, Tamara and Filipovi\'{c}, Nenad}, year = {2021}, pages = {13}, DOI = {10.1016/j.molstruc.2021.130512}, chapter = {130512}, keywords = {Hydrazonyl–thiazoles, Single crystal X-ray analysis, Antiproliferative activity, Antioxidant activity, Drug likeness parameters, DFT}, journal = {Journal of molecular structure}, doi = {10.1016/j.molstruc.2021.130512}, volume = {1240}, issn = {0022-2860}, title = {Structural, antioxidant, antiproliferative, and in-silico study of pyridine-based hydrazonyl- selenazoles and their sulphur isosteres}, keyword = {Hydrazonyl–thiazoles, Single crystal X-ray analysis, Antiproliferative activity, Antioxidant activity, Drug likeness parameters, DFT}, chapternumber = {130512} }
@article{article, author = {Ara\v{s}kov, Jovana and Nikoli\'{c}, Milan and Armakovi\'{c}, Stevan and Rodi\'{c}, Marko and Vi\v{s}njevac, Aleksandar and Padron, Jose and Todorovi\'{c}, Tamara and Filipovi\'{c}, Nenad}, year = {2021}, pages = {13}, DOI = {10.1016/j.molstruc.2021.130512}, chapter = {130512}, keywords = {Hydrazonyl–thiazoles, Single crystal X-ray analysis, Antiproliferative activity, Antioxidant activity, Drug likeness parameters, DFT}, journal = {Journal of molecular structure}, doi = {10.1016/j.molstruc.2021.130512}, volume = {1240}, issn = {0022-2860}, title = {Structural, antioxidant, antiproliferative, and in-silico study of pyridine-based hydrazonyl- selenazoles and their sulphur isosteres}, keyword = {Hydrazonyl–thiazoles, Single crystal X-ray analysis, Antiproliferative activity, Antioxidant activity, Drug likeness parameters, DFT}, chapternumber = {130512} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus

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