A Homozygous Dab1−/− Is a Potential Novel Cause of Autosomal Recessive Congenital Anomalies of the Mice Kidney and Urinary Tract

Racetin, Anita; Filipović, Natalija; Lozić, Mirela; Ogata, Masaki; Larissa, Gudelj Ensor; Kelam, Nela; Kovačević, Petra; Watanabe, Koichiro; Katsuyama, Yu; Saraga-Babić, Mirna; Glavina Durdov, Merica; Vukojević, Katarina

doi:10.3390/biom11040609

Pregled bibliografske jedinice broj: 1123645

A Homozygous Dab1−/− Is a Potential Novel Cause of Autosomal Recessive Congenital Anomalies of the Mice Kidney and Urinary Tract

Racetin, Anita; Filipović, Natalija; Lozić, Mirela; Ogata, Masaki; Larissa, Gudelj Ensor; Kelam, Nela; Kovačević, Petra; Watanabe, Koichiro; Katsuyama, Yu; Saraga-Babić, Mirna et al.

A Homozygous Dab1−/− Is a Potential Novel Cause of Autosomal Recessive Congenital Anomalies of the Mice Kidney and Urinary Tract // Biomolecules, 11 (2021), 4; 609, 14 doi:10.3390/biom11040609 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1123645 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
A Homozygous Dab1−/− Is a Potential Novel Cause of Autosomal Recessive Congenital Anomalies of the Mice Kidney and Urinary Tract

Autori
Racetin, Anita ; Filipović, Natalija ; Lozić, Mirela ; Ogata, Masaki ; Larissa, Gudelj Ensor ; Kelam, Nela ; Kovačević, Petra ; Watanabe, Koichiro ; Katsuyama, Yu ; Saraga-Babić, Mirna ; Glavina Durdov, Merica ; Vukojević, Katarina

Izvornik
Biomolecules (2218-273X) 11 (2021), 4; 609, 14

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
yotari ; kidney function ; postnatal kidney development ; immunofluorescence staining ; transmission electron microscopy

Sažetak
This study aimed to explore morphology changes in the kidneys of Dab1−/− (yotari) mice, as well as expression patterns of reelin, NOTCH2, LC3B, and cleaved caspase3 (CASP3) proteins, as potential determinants of normal kidney formation and function. We assumed that Dab1 functional inactivation may cause disorder in a wide spectrum of congenital anomalies of the kidney and urinary tract (CAKUT).

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA

Projekti:
HRZZ-IP-2016-06-2575 - Karakterizacija kandidat gena za kongenitalne anomalije bubrega i urotrakta (CAKUT) tijekom razvoja u miša i čovjeka (CAKUT) (Vukojević, Katarina, HRZZ ) ( CroRIS)

Ustanove:
KBC Split,
Medicinski fakultet, Split

Profili:

Mirna Saraga-Babić (autor)