Naslov
Oxidative Stress in Ischemic Heart Disease

Autori
Kibel, Aleksandar ; Lukinac, Ana Marija ; Dambic, Vedran ; Juric, Iva ; Selthofer-Relatic, Kristina

Izvornik
Oxidative medicine and cellular longevity (1942-0900) 2020 (2020); 1-30

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, ostalo

Ključne riječi
oxidative stress, atherosclerosis, ischemic heart disease

Sažetak
One of the novel interesting topics in the study of cardiovascular disease is the role of the oxidation system, since inflammation and oxidative stress are known to lead to cardiovascular diseases, their progression and complications. During decades of research, many complex interactions between agents of oxidative stress, oxidation, and antioxidant systems have been elucidated, and numerous important pathophysiological links to na number of disorders and diseases have been established. This review article will present the most relevant knowledge linking oxidative stress to vascular dysfunction and disease. The review will focus on the role of oxidative stress in endotheleial dysfunction, atherosclerosis, and other pathogenetic processes and mechanisms that contribute to the development of ischemic heart disease.

Izvorni jezik
Engleski

POVEZANOST RADA