Pregled bibliografske jedinice broj: 1120603
Erythrocytosis and thrombocytosis secondary to hyperandrogenism caused by ovarian Leydig cell tumor
Erythrocytosis and thrombocytosis secondary to hyperandrogenism caused by ovarian Leydig cell tumor // Endocrine oncology and metabolism, 3 (2017), 4; 124-126 doi:10.21040/eom/2017.3.4.6 (međunarodna recenzija, članak, stručni)
CROSBI ID: 1120603 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Erythrocytosis and thrombocytosis secondary to
hyperandrogenism caused by ovarian Leydig cell
tumor
Autori
Mirošević, Gorana ; Butorac, Dražan ; Kruljac, Ivan ; Vrkljan, Milan
Izvornik
Endocrine oncology and metabolism (1849-8922) 3
(2017), 4;
124-126
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni
Ključne riječi
testosterone, hematopoesis, erytrocytosis, trombocytosis, Leydig cell tumor
Sažetak
Both erytroblasts and megakaryocytes contain androgen receptors, and testosterone regulates their expression. However, the exact mechanisms of testosterone's hematopoietic effects are poorly understood. We report a case of perimenopausal woman with severe hyperandrogenism caused by pure Leydig cell ovarian tumor accompanied by concomitant erythrocytosis and thrombocytosis. Substantial, immediate, and persistent decrease in both red blood cell count and platelet count after testosterone-secreting tumor removal in our patient suggests testosterone's synergistic effect on erythropoiesis and thrombopoiesis.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
KBC "Sestre Milosrdnice"
