Naslov
Emerging Natural-Product-Based Treatments for the Management of Osteoarthritis

Autori
Pérez-Lozano, Maria-Luisa ; Cesaro, Annabelle ; Mazor, Marija ; Esteve, Eric ; Berteina-Raboin, Sabine ; Best, Thomas M. ; Lespessailles, Eric ; Toumi, Hechmi

Izvornik
Antioxidants (2076-3921) 10 (2021), 2; 265, 27

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
osteoarthritis ; natural products ; cartilage ; bone

Sažetak
Osteoarthritis (OA) is a complex degenerative disease in which joint homeostasis is disrupted, leading to synovial inflammation, cartilage degradation, subchondral bone remodeling, and resulting in pain and joint disability. Yet, the development of new treatment strategies to restore the equilibrium of the osteoarthritic joint remains a challenge. Numerous studies have revealed that dietary components and/or natural products have anti-inflammatory, antioxidant, anti- boneresorption, and anabolic potential and have received much attention toward the development of new therapeutic strategies for OA treatment. In the present review, we provide an overview of current and emerging natural-product-based research treatments for OA management by drawing attention to experimental, pre- clinical, and clinical models. Herein, we review current and emerging natural-product- based research treatments for OA management.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA