Pretraga

Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1110238

Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources

Bovo, Samuele; Schiavo, Giuseppina; Ribani, Anisa; Utzeri, Valerio J.; Taurisano, Valeria; Ballan, Mohamad; Muñoz, Maria; Alves, Estefania; Araujo, Jose P.; Bozzi, Riccardo et al.
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources // Scientific reports, 11 (2021), 3359, 13 doi:10.1038/s41598-021-82956-0 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 1110238 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources

Autori
Bovo, Samuele ; Schiavo, Giuseppina ; Ribani, Anisa ; Utzeri, Valerio J. ; Taurisano, Valeria ; Ballan, Mohamad ; Muñoz, Maria ; Alves, Estefania ; Araujo, Jose P. ; Bozzi, Riccardo ; Charneca, Rui ; Di Palma, Federica ; Djurkin Kušec, Ivona ; Etherington, Graham ; Fernandez, Ana I. ; García, Fabián ; García‑Casco, Juan ; Karolyi, Danijel ; Gallo, Maurizio ; Martins, José Manuel ; Mercat, Marie‑José ; Núñez, Yolanda ; Quintanilla, Raquel ; Radović, Čedomir ; Razmaite, Violeta ; Riquet, Juliette ; Savić, Radomir ; Škrlep, Martin ; Usai, Graziano ; Zimmer, Christoph ; Ovilo, Cristina ; Fontanesi, Luca

Izvornik
Scientific reports (2045-2322) 11 (2021); 3359, 13

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
pig ; local breed ; whole genome sequencing ; coronavirus

Sažetak
Coronaviruses silently circulate in human and animal populations, causing mild to severe diseases. Therefore, livestock are important components of a “One Health” perspective aimed to control these viral infections. However, at present there is no example that considers pig genetic resources in this context. In this study, we investigated the variability of four genes (ACE2, ANPEP and DPP4 encoding for host receptors of the viral spike proteins and TMPRSS2 encoding for a host proteinase) in 23 European (19 autochthonous and three commercial breeds and one wild boar population) and two Asian Sus scrofa populations. A total of 2229 variants were identified in the four candidate genes: 26% of them were not previously described ; 29 variants affected the protein sequence and might potentially interact with the infection mechanisms. The results coming from this work are a first step towards a “One Health” perspective that should consider conservation programs of pig genetic resources with twofold objectives: (i) genetic resources could be reservoirs of host gene variability useful to design selection programs to increase resistance to coronaviruses ; (ii) the described variability in genes involved in coronavirus infections across many different pig populations might be part of a risk assessment including pig genetic resources.

Izvorni jezik
Engleski

Znanstvena područja
Interdisciplinarne prirodne znanosti, Poljoprivreda (agronomija)



POVEZANOST RADA

Ustanove:
Fakultet agrobiotehničkih znanosti Osijek,
Agronomski fakultet, Zagreb

Profili:

Avatar Url Ivona Djurkin Kušec (autor)

Avatar Url Danijel Karolyi (autor)

Poveznice na cjeloviti tekst rada:

Pristup cjelovitom tekstu rada doi www.nature.com

Citiraj ovu publikaciju:

Bovo, Samuele; Schiavo, Giuseppina; Ribani, Anisa; Utzeri, Valerio J.; Taurisano, Valeria; Ballan, Mohamad; Muñoz, Maria; Alves, Estefania; Araujo, Jose P.; Bozzi, Riccardo et al.
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources // Scientific reports, 11 (2021), 3359, 13 doi:10.1038/s41598-021-82956-0 (međunarodna recenzija, članak, znanstveni)
Bovo, S., Schiavo, G., Ribani, A., Utzeri, V., Taurisano, V., Ballan, M., Muñoz, M., Alves, E., Araujo, J. & Bozzi, R. (2021) Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources. Scientific reports, 11, 3359, 13 doi:10.1038/s41598-021-82956-0.
@article{article, author = {Bovo, Samuele and Schiavo, Giuseppina and Ribani, Anisa and Utzeri, Valerio J. and Taurisano, Valeria and Ballan, Mohamad and Mu\~{n}oz, Maria and Alves, Estefania and Araujo, Jose P. and Bozzi, Riccardo and Charneca, Rui and Di Palma, Federica and Djurkin Ku\v{s}ec, Ivona and Etherington, Graham and Fernandez, Ana I. and Garc\'{\i}a, Fabi\'{a}n and Garc\'{\i}a‑Casco, Juan and Karolyi, Danijel and Gallo, Maurizio and Martins, Jos\'{e} Manuel and Mercat, Marie‑Jos\'{e} and N\'{u}\~{n}ez, Yolanda and Quintanilla, Raquel and Radovi\'{c}, \v{C}edomir and Razmaite, Violeta and Riquet, Juliette and Savi\'{c}, Radomir and \v{S}krlep, Martin and Usai, Graziano and Zimmer, Christoph and Ovilo, Cristina and Fontanesi, Luca}, year = {2021}, pages = {13}, DOI = {10.1038/s41598-021-82956-0}, chapter = {3359}, keywords = {pig, local breed, whole genome sequencing, coronavirus}, journal = {Scientific reports}, doi = {10.1038/s41598-021-82956-0}, volume = {11}, issn = {2045-2322}, title = {Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources}, keyword = {pig, local breed, whole genome sequencing, coronavirus}, chapternumber = {3359} }
@article{article, author = {Bovo, Samuele and Schiavo, Giuseppina and Ribani, Anisa and Utzeri, Valerio J. and Taurisano, Valeria and Ballan, Mohamad and Mu\~{n}oz, Maria and Alves, Estefania and Araujo, Jose P. and Bozzi, Riccardo and Charneca, Rui and Di Palma, Federica and Djurkin Ku\v{s}ec, Ivona and Etherington, Graham and Fernandez, Ana I. and Garc\'{\i}a, Fabi\'{a}n and Garc\'{\i}a‑Casco, Juan and Karolyi, Danijel and Gallo, Maurizio and Martins, Jos\'{e} Manuel and Mercat, Marie‑Jos\'{e} and N\'{u}\~{n}ez, Yolanda and Quintanilla, Raquel and Radovi\'{c}, \v{C}edomir and Razmaite, Violeta and Riquet, Juliette and Savi\'{c}, Radomir and \v{S}krlep, Martin and Usai, Graziano and Zimmer, Christoph and Ovilo, Cristina and Fontanesi, Luca}, year = {2021}, pages = {13}, DOI = {10.1038/s41598-021-82956-0}, chapter = {3359}, keywords = {pig, local breed, whole genome sequencing, coronavirus}, journal = {Scientific reports}, doi = {10.1038/s41598-021-82956-0}, volume = {11}, issn = {2045-2322}, title = {Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resources}, keyword = {pig, local breed, whole genome sequencing, coronavirus}, chapternumber = {3359} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

Citati:

    Altmetrijski pokazatelji:


    Podijeli:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font
    CROSBI koristi kolačiće (cookies) kako bi poboljšao funkcionalnost stranice.