Pregled bibliografske jedinice broj: 1110057
A prospective characterization of the resolution of ixabepilone induced peripheral neuropathy: dana from a large registrational program in patients with metastatic breast cancer
A prospective characterization of the resolution of ixabepilone induced peripheral neuropathy: dana from a large registrational program in patients with metastatic breast cancer // Breast Cancer
Hrvatska, 2008. str. 256-258 (poster, nije recenziran, sažetak, znanstveni)
CROSBI ID: 1110057 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
A prospective characterization of the
resolution of ixabepilone induced peripheral
neuropathy: dana from a large registrational
program in patients with metastatic breast
cancer
Autori
Perez E., Pivot X., Vrdoljak E., Sparano JA., Vogel C., Peck R., Mukhopadhyay P., Vahdat L.
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Breast Cancer
/ - , 2008, 256-258
Skup
BREAST CANCER 2008.
Mjesto i datum
Hrvatska, 2008
Vrsta sudjelovanja
Poster
Vrsta recenzije
Nije recenziran
Ključne riječi
ixabepilone metastatic breast cancer
Sažetak
Dose-limiting neuropathy is a major adverse event associated with most of the microtubule- stabilizing agent-based chemotherapy regimens. Ixabepilone, a semisynthetic analogue of the natural epothilone B, has activity against a wide range of tumor types. Peripheral neuropathy (PN), associated with ixabepilone treatment, is usually mild to moderate, predominantly sensory and cumulative. Preclinical studies demonstrate that ixabepilone and taxanes produce a similar neurotoxicity profile.
Izvorni jezik
Engleski
