Pregled bibliografske jedinice broj: 1108408
Mechanobiology of the Mitotic Spindle
Mechanobiology of the Mitotic Spindle // Developmental cell, 56 (2021), 2; 192-201 doi:10.1016/j.devcel.2020.11.003 (međunarodna recenzija, pregledni rad, ostalo)
CROSBI ID: 1108408 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Mechanobiology of the Mitotic Spindle
Autori
Pavin, Nenad ; Tolić, Iva M.
Izvornik
Developmental cell (1534-5807) 56
(2021), 2;
192-201
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, ostalo
Ključne riječi
mitotic spindle ; microtubules ; kinetochores ; kinetochore fibers ; bridging fibers ; kinesins ; forces ; laser ablation ; microneedle ; theory ; modeling
Sažetak
The mitotic spindle is a microtubule-based assembly that separates the chromosomes during cell division. As the spindle is basically a mechanical micro machine, the understanding of its functioning is constantly motivating the development of experimental approaches based on mechanical perturbations, which are complementary to and work together with the classical genetics and biochemistry methods. Recent data emerging from these approaches in combination with theoretical modeling led to novel ideas and significant revisions of the basic concepts in the field. In this Perspective, we discuss the advances in the understanding of spindle mechanics, focusing on microtubule forces that control chromosome movements.
Izvorni jezik
Engleski
Znanstvena područja
Fizika, Biologija, Interdisciplinarne prirodne znanosti
POVEZANOST RADA
Ustanove:
Institut "Ruđer Bošković", Zagreb,
Prirodoslovno-matematički fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
