Naslov
Progress and trends in pediatric hematopoietic cell transplantation in Central-East European
(Progress and trends in pediatric hematopoietic cell transplantation in Central-East European countries)

Autori
Czyżewski, Krzysztof ; Sedláček, Petr ; Štěrba, Jaroslav ; Bilic, Ernest ; Roganović, Jelena ; Krivan, Gergely ; Rascon, Jelena ; Colita, Anca ; Jazbec, Janez ; Švec, Peter ; Serhii, Pavlyk ; Lysytsia, Oleksandr ; Wachowiak, Jacek ; Styczyński, Jan

Izvornik
Acta Haematologica Polonica (2300-7117) 51 (2020), 3; 142-150

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
hematopoietic cell transplantation ; children ; Central-Eastern European countries

Sažetak
Hematopoietic cell transplantation (HCT) is widely used as a treatment for acquired and congenital disorders. In recent years, a significant increase in transplant activity around the world has been observed, especially in Eastern European countries. This article aimed to assess progress and trends in pediatric HCT in Central-Eastern European countries between 2013 and 2018. Transplant activity survey in 2013 and 2018 in nine Central-Eastern European countries (Czech Republic, Croatia, Hungary, Lithuania, Poland, Romania, Slovakia, Slovenia, and Ukraine) was performed. The highest transplant rates in total were found in the Czech Republic and Hungary. When calculated per 10 million of the pediatric population, a 25.9% increase in the number of allo-HCT was observed with the highest in Croatia, Romania, Lithuania, and Poland ; and a 12.2% increase in the number of auto-HCT was observed with the highest in Slovenia, Slovakia, Romania, Poland, Ukraine, and Croatia. We have shown, over the years 2013 and 2018, in some countries of Central-Eastern Europe that there was a significant increase in transplant activity, especially in those with the lower rates. This increase was observed mainly in centers already existing in 2013, especially in the allo-HCT setting. The rise of activity was significantly less influenced by the creation of new transplant centers or the increase in the number of pediatric transplant beds. In conclusion, our analysis indicates that in the Czech Republic, Hungary, Lithuania, and Slovenia, the actual infrastructure and the number of HCTs cover the needs, whereas in other countries, especially in Romania and Ukraine, the number of HCT needs to be increased

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA