Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1106406

Diagnostic and prognostic value of sCD14-ST--presepsin for patients admitted to hospital intensive care unit (ICU)


Godnic, Matej; Stubljar, David; Skvarc, Miha; Jukic, Tomislav
Diagnostic and prognostic value of sCD14-ST--presepsin for patients admitted to hospital intensive care unit (ICU) // Wiener klinische Wochenschrift, 127 (2015), 13-14; 521-527 doi:10.1007/s00508-015-0719-5 (međunarodna recenzija, članak, ostalo)


CROSBI ID: 1106406 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Diagnostic and prognostic value of sCD14-ST--presepsin for patients admitted to hospital intensive care unit (ICU)
(Diagnostic and prognostic value of sCD14-ST—presepsin for patients admitted to hospital intensive care unit (ICU))

Autori
Godnic, Matej ; Stubljar, David ; Skvarc, Miha ; Jukic, Tomislav

Izvornik
Wiener klinische Wochenschrift (0043-5325) 127 (2015), 13-14; 521-527

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
Inflammatory biomarkers ; Infection ; SCD14-ST ; CD64 ; CRP ; PCT ; Sepsis recognition

Sažetak
Background: Sepsis is a serious problem in intensive care units all over the world. Biomarkers could be useful to identify patients at risk. We focused especially on the performance of presepsin (sCD14-ST), compared to C-reactive protein (CRP), procalcitonin (PCT) and CD64, to determine its diagnostic and prognostic indications. Methods: The study was conducted on 47 hospitalized patients after procedures, who were divided into three groups ; systemic inflammatory response (SIRS), sepsis and septic shock. Expression of CD64 on neutrophils presented as CD64 index, sCD14-ST, CRP and PCT were measured in whole blood or plasma samples. All patients had standard samples like urine, respiratory tract samples etc. taken for culturing. Blood cultures were drawn to confirm bloodstream infection. Results: Forty (85 %) patients had SIRS with bacterial infection and seven (15 %) patients had SIRS with no infection. All infections were confirmed with blood cultures. Biomarkers were evaluated in all patients. In patients with confirmed infection the values were high. The patients with bacterial infection showed statistical significance with CD64 index (p = 0.003), CRP (p = 0.049) and sCD14-ST (p = 0.026), but not with PCT (p = 1.000). The severity of diagnosed SIRS was significant only with PCT (p < 0.001). Conclusion: CD64 index, CRP and sCD14-ST served as good parameters to determine possible infection in patients that needed intensive care after major procedures. Values of PCT were the only ones to predict SIRS severity and could distinguish between sepsis and severe sepsis or septic shock.

Izvorni jezik
Engleski



POVEZANOST RADA


Profili:

Avatar Url Tomislav Jukić (autor)

Poveznice na cjeloviti tekst rada:

doi

Citiraj ovu publikaciju:

Godnic, Matej; Stubljar, David; Skvarc, Miha; Jukic, Tomislav
Diagnostic and prognostic value of sCD14-ST--presepsin for patients admitted to hospital intensive care unit (ICU) // Wiener klinische Wochenschrift, 127 (2015), 13-14; 521-527 doi:10.1007/s00508-015-0719-5 (međunarodna recenzija, članak, ostalo)
Godnic, M., Stubljar, D., Skvarc, M. & Jukic, T. (2015) Diagnostic and prognostic value of sCD14-ST--presepsin for patients admitted to hospital intensive care unit (ICU). Wiener klinische Wochenschrift, 127 (13-14), 521-527 doi:10.1007/s00508-015-0719-5.
@article{article, author = {Godnic, Matej and Stubljar, David and Skvarc, Miha and Jukic, Tomislav}, year = {2015}, pages = {521-527}, DOI = {10.1007/s00508-015-0719-5}, keywords = {Inflammatory biomarkers, Infection, SCD14-ST, CD64, CRP, PCT, Sepsis recognition}, journal = {Wiener klinische Wochenschrift}, doi = {10.1007/s00508-015-0719-5}, volume = {127}, number = {13-14}, issn = {0043-5325}, title = {Diagnostic and prognostic value of sCD14-ST--presepsin for patients admitted to hospital intensive care unit (ICU)}, keyword = {Inflammatory biomarkers, Infection, SCD14-ST, CD64, CRP, PCT, Sepsis recognition} }
@article{article, author = {Godnic, Matej and Stubljar, David and Skvarc, Miha and Jukic, Tomislav}, year = {2015}, pages = {521-527}, DOI = {10.1007/s00508-015-0719-5}, keywords = {Inflammatory biomarkers, Infection, SCD14-ST, CD64, CRP, PCT, Sepsis recognition}, journal = {Wiener klinische Wochenschrift}, doi = {10.1007/s00508-015-0719-5}, volume = {127}, number = {13-14}, issn = {0043-5325}, title = {Diagnostic and prognostic value of sCD14-ST—presepsin for patients admitted to hospital intensive care unit (ICU)}, keyword = {Inflammatory biomarkers, Infection, SCD14-ST, CD64, CRP, PCT, Sepsis recognition} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font