Pregled bibliografske jedinice broj: 1101966
Suicidality and epilepsy: A neuropsychobiological perspective
Suicidality and epilepsy: A neuropsychobiological perspective // Epilepsy & Behavior, 22 (2011), 1; 77-84 doi:10.1016/j.yebeh.2011.04.059 (međunarodna recenzija, članak, ostalo)
CROSBI ID: 1101966 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Suicidality and epilepsy: A neuropsychobiological
perspective
Autori
Hecimovic, Hrvoje ; Salpekar, Jay ; Kanner, Andres M. ; Barry, John J.
Izvornik
Epilepsy & Behavior (1525-5050) 22
(2011), 1;
77-84
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo
Ključne riječi
epilepsy
Sažetak
People with epilepsy (PWE) are at increased risk of experiencing suicidal ideation, displaying suicidal behavior, and committing suicide than the general population. The relationship between suicidality and epilepsy is complex and multifactorial in which operant pathogenic mechanisms include epilepsy-related variables, personal and familial psychiatric history, and iatrogenic effects. Furthermore, a bidirectional relationship between suicidality and epilepsy has suggested the existence of common neurobiological pathogenic mechanisms operant in both conditions and including disturbances of several neurotransmitters, in particular, serotonin (5HT), norepinephrine (NE), glutamate (GTE), and γ-aminobutyric acid (GABA), and disturbances of the hypothalamic- pituitary-adrenal axis (HPAA), which, in turn, can result in abnormal secretion of some of these neurotransmitters. The purpose of this article is to review these common neurobiological pathogenic mechanisms.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
