Naslov
Increased Bone Turnover Markers after Renal Transplantation

Autori
Gršković, Antun ; Ćelić, Tanja ; Fučkar, Dora ; Markić Dean ; Trošelj, Marin ; Bobinac, Dragica

Izvornik
Collegium antropologicum. Supplement (0353-3735) 34 (2010), Suppl 2; 145-148

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
chronic renal failure, renal transplantation, bone markers

Sažetak
Bone remodeling is a process that occurs continuously in a seemingly inactive tissue like bone. Because of decreased vitamin D synthesis, phosphorus retention and decreased calcium blood concentration, patients with chronic renal failure (CRF) develop secondary hyperparathyroidism1–5. Elevated PTH levels shifts balance between osteoblast and osteoclast activity in favor of osteoclast activity and, therefore, bone resorption. Bone metabolic disorder that affects patients with CRF is called renal osteodystrophy (ROD)1–5. We presume that renal transplantation reverses bone metabolism disorder and our goal was to establish whether osteoblast and osteoclast activity returns to the levels of healthy individuals.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA