Naslov
Body mass index: short- and long-term impact on kidney transplantation

Autori
Orlic, Lidija ; Mikolasevic, Ivana ; Jakopcic, Ivan ; Grskovic, Antun ; Jelic Pranjic, Ita ; Racki, Sanjin ; Stimac, Davor

Izvornik
International Journal of Clinical Practice (1368-5031) 69 (2015), 11; 1357-1365

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
kidney transplantation ; body mass index ; overweight ; obesity ; outcomes

Sažetak
The topic of pretransplantation body mass index (BMI) is still a matter of controversy. The aim of this study was to investigate the influence of pre transplant BMI on short and long-term outcomes in patients receiving kidney transplant. We have analyzed 521 renal transplant recipients (RTRs). BMI was categorized as follows: less than or equal to 20, more than 20 to less than or equal to 25, more than 25 to less than or equal to 30 and more than 30. The distribution of the RTRs per category of BMI at baseline was: ≤ 20 (14.4%), > 20 to ≤ 25 (50.9%), > 25 ≤ 30 (26.9%) and > 30 (7.9%). In further analysis the patients were stratified into four groups according to their pre transplant BMI values. There was no difference in the rates of delayed graft function between the four analyzed groups of patients. Recipients with normal pre transplant BMI were less likely to develop wound complications in comparison to the recipients with high BMI (p=0.04) and obese recipients (p=0.0001). RTRs with normal BMI were less likely to develop lymphoceles in comparison to the recipients with high BMI (p=0.0003). Obese patients were more likely to develop lymphocele in comparison to the recipients with high BMI (p=0.01). Obese recipients had a longer mean length of hospital stay in comparison to the recipients with normal BMI (p=0.04). There was no significant difference regarding one-year graft and patient survival, as well as due to acute rejection crisis between the investigated groups of recipients. We did not find any significant difference in 5-years patients and graft survival between those RTRs with BMI > 20 to ≤ 25 and to those recipients with BMI > 25. Overweight and obese transplant candidates should not be excluded from kidney transplantation.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

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