Naslov
Short-term treatment of pertussis with azithromycin in infants and young children

Autori
Baće, Ana ; Zrnić, T. ; Begovac, Josip ; Kuzmanović, N. ; Culig, Josip

Izvornik
European journal of clinical microbiology & infectious diseases (0934-9723) 18 (1999), 4; 296-298

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
nfants ; children ; pertussis ; azithromycin

Sažetak
A prospective, open, noncomparative study was conducted to assess the efficacy and safety of azithromycin given once daily for 3 or 5 days to eradicate Bordetella pertussis from the upper respiratory tract of infants and young children. Seventeen children received azithromycin in a dose of 10 mg/kg on day 1 followed by 5 mg/kg once daily for four consecutive days, and 20 were given 10 mg/kg once daily for 3 days. Seven days after the initiation of therapy, 33 of 35 (94.3%) patients had negative cultures for Bordetella pertussis. On day 14, cultures from all 34 evaluable patients were negative. These findings suggest that a controlled, comparative study of erythromycin versus short-term administration of azithromycin is justified.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA