Naslov
CHURG-STRAUSS SYNDROME: A CASE REPORT

Autori
Stipić Marković, Asja ; Stipić, Jagoda ; Crnčević-Urek, Marija ; Crnek-Kunstelj, Vesna

Izvornik
Acta clinica Croatica (0353-9466) 41 (2002); 95-98

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, prikaz, stručni

Ključne riječi
Churg-Strauss syndrome: Churg Churg-Strauss syndrome-diagnosis; Treatment-

Sažetak
Churg-Strauss syndrome (CSS) is a necrotizing small vessel vasculitis characterized by the presence asthma, hypereosinophilia and sinusitis. Other common manifestations are pulmonary infiltrates, skin, gastrointestinal and cariovascular involvement. Although not a criterion for the diagnosis of CSS, the presence of antineutrophil cytoplasmic autoantibodies (ANCA) is now established as being associated with CSS. In this report, a 31-year-old male with a history of diffcut-to-control asthma is presented. It was associated with peripheral and bronchoalveolar eosinophilia, sinusitis, and high Ievel of ANCA (perinuclear labeling pattern). Clinical manifestations observed at the time of relapses were palpable purpura, erythema nodosum, arthralgia, musculoskeletal complications, and episcleritis.ln spite of vasculitis remission, low doses of steroids to control asthma were necessary for 10 years. The aim of this case report is to point to the possibility of CSS in patients with severe persistent asthma and atypical allergic diathesis.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA