Naslov
˝ Depression and circadian typology˝

Autori
Bielen, Jelena ; Melada, Anja ; Jakšić, Nenad ; Markelić, Ivona ; Jakovljević, Miro

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
1st International Conference on Creative Psychopharmacotherapy, 14th Central European Neuropsychopharmacological Symposium ; 6th Croatian Congress of Psychopharmacotherapy Abstract book / - , 2013, 1-1

Skup
1st International Conference on Creative Psychopharmacotherapy, 14th Central European Neuropsychopharmacological Symposium ; 6th Croatian Congress of Psychopharmacotherapy

Mjesto i datum
Dubrovnik, Hrvatska, 25.09.2013. - 28.09.2013

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
depression - circadian rhythm - circadian typology – morning - evening

Sažetak
Introduction: Circadian rhythms include all physiological processes displaying a period around 24 hours. Sleep/wake cycles, body temperature, hormone secretion and other functions are subjected to person’s individual circadian rhythm. Circadian typology includes three chronotypes: morning, neither and evening. Aim: The aim of this study was to examine the chronobiological aspects of depression. Methods: PARTICIPANTS: 60 patients suffering from depressioN treated as outpatients at the Department of Psychiatry were compared to a control group consisting of 50 medical workers employed at the University Hospital Centre Zagreb. MEASURE: The study used a self-report measure of circadian typology was utilized - the Morningness-Eveningness Questionnaire (MEQ). MEQ:MEQ consists of 21 items and its objective is to depict patients’ sleeping habits as well as their mood and physical activities. The answer options include using visual analog scale and choosing between four or five answer options. Results: According to our findings, among depressed patients 35% were morning, 58.3% neither and 6.7% evening types. In the control group 46% were morning, 48% neither and 6.0% evening types. Depressed patients reported stronger morning fatigue. Further, they tended to go to sleep earlier and felt more tired earlier in the evening, and they were less prone to choosing morning periods for completing complex cognitive tasks. Conclusion: This study supports the association between depression and some alterations in circadian rhythms of behavior and sleep. Depression may be considered as the consequence or trigger of circadian disturbances. However, both depression and circadian rhythm disturbances may have a common aetiology: a decreased cellular resilience associated with lower resistance to stressful events. We are still at the beginning of understanding the association between circadian disruption and depression and there is still a lot of research to be done particularly regarding the specific chronotypes. Treating depression pharmacologicaly through the restoration of circadian rhythms may open a new era in clinical practice of superior management of depression.

Izvorni jezik
Engleski

POVEZANOST RADA