Pregled bibliografske jedinice broj: 108475
Pentylenetetrazol-induced seizures and kindling: changes in free fatty acids, superoxide dismutase, and glutathione peroxidase activity
Pentylenetetrazol-induced seizures and kindling: changes in free fatty acids, superoxide dismutase, and glutathione peroxidase activity // Neurochemistry International, 42 (2003), 2; 173-178 doi:10.1016/S0197-0186(02)00070-0 (međunarodna recenzija, članak, znanstveni)
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Naslov
Pentylenetetrazol-induced seizures and kindling: changes in free fatty acids, superoxide dismutase, and glutathione peroxidase activity
Autori
Eraković, Vesna ; Župan, Gordana ; Varljen, Jadranka ; Simonić, Ante
Izvornik
Neurochemistry International (0197-0186) 42
(2003), 2;
173-178
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Free fatty acids ; Glutathione peroxidase ; Pentylenetetrazol kindling ; Rat ; Superoxide dismutase
Sažetak
The whole brain free fatty acid (FFA) level, as well as the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPX) were determined in the frontal cortex, cerebellum, hippocampus, and pons-medulla region of the single pentylenetetrazol (PZT)-treated and PZT-kindled Hannover-Wistar rats. PZT administration in the convulsive dose caused significant increase of the brain FFA content. Decreased SOD activity was detected in the frontal cortex of PZT-kindled rats, whereas decreased GPX activity was found in the frontal cortex and cerebellum of all treated rats, as well as in the hippocampus and pons-medulla of PZT-kindled rats. Kindling caused distinctive change of antioxidative defense in the frontal cortex, hippocampus, and pons-medulla region.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Rijeka
Profili:
Ante Simonić
(autor)
Jadranka Varljen
(autor)
Gordana Župan
(autor)
Vesna Eraković Haber
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- Chemical Abstracts
- BIOSIS
- EMBASE
- Elsevier BIOBASE
- MEDLINE
- PASCAL
- Psychology Abstracts
- Research Alert
- Scopus