Naslov
Preparation of new functionalized thienyl bicyclo[3.2.1]octadienes

Autori
Vuk Dragana ; Škorić, Irena ; Milašinović, Valentina ; Molčanov, Krešimir ; Marinić, Željko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
18. Ružičkini dani "Danas znanost - sutra industrija"

Mjesto i datum
Vukovar, Hrvatska, 16.09.2020. - 18.09.2020

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
bicyclo[3.2.1]octadiene ; photocyclization ; thiophene

Sažetak
The aim of this study is to prepare novel thiophene bicyclo[3.2.1]octadiene derivatives with structure convenient for the introduction of new functional groups. Further on, the study aims at expanding the compound library and at creating preconditions for further biological investigations. The starting substrates were easily obtained by Vilsmeier-Haack’s reaction of bicyclo[3.2.1]octadiene thiophene derivatives From the obtained carbaldehydes, novel methyl-, methoxy- and cyano-substituted styryl thieno-benzobicyclo[3.2.1]octadiene derivatives were formed by Wittig's reaction and subjected to photochemical reactions, in terms of obtaining new annulated structures. As a part of this study, aldol reaction of starting 2-substituted carbaldehyde and acetone was also performed, which produced the thieno-fused benzobicyclo[3.2.1]octadiene compound with an extended conjugation.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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