Naslov
Alloimunization following allogeneic hematopoietic stem cell transplantation

Autori
Raos, Mirela ; Bojanic, Ines ; Serventi Seiwerth, Ranka ; Golubic Cepulic, Branka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the 35th international congress of the ISBT, Vox Sanguinis. 2018 ; 113(S1) / - , 2018, 225-226

Skup
35th International Congress of the ISBT

Mjesto i datum
Toronto, Kanada, 02.06.2018. - 06.06.2018

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Allogeneic hematopoietic stem cell transplantation ; alloimmunization

Sažetak
In almost all patients treated with allogeneic hematopoietic stem cell transplantation (HSCT), there is a certain degree of disparity in red blood cell (RBC) antigens. Major, minor and bidirectional ABO incompatibility can cause acute hemolysis or delayed erythropoiesis recovery in the post-transplant period. Non- ABO red blood cell alloantibodies may cause similar complications if the recipient or donor RBC expresses a specific antigen. New immunization after allogeneic HSCT, although rare in occurrence (1 to 8.7%), can also cause hemolysis. Aims: The aim was to investigate the frequency of non-ABO alloimmunization following allogeneic HSCT, the cause of their occurrence and the specificity of alloantibodies.

Izvorni jezik
Engleski

POVEZANOST RADA