Naslov
Autoimmune hemolytic anemia: Serological characterstics and transfusion challenges

Autori
Raos, Mirela ; Pulanic, Drazen ; Lukic, Marija ; Vinkovic, Matea ; Kilic Paula ; Tomac, Gordana ; Vidovic, Ivana ; Golubic Cepulic, Branka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Vox Sanguinis / - , 2019, 44-44

Skup
29th Regional Congress of the ISBT

Mjesto i datum
Basel, Švicarska, 22.06.2019. - 26.06.2019

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Autoimmune hemolytic anemia ; serological charactersitics ; transfusion

Sažetak
Autoimmune hemolytic anemia (AIHA) is a rare autoimmune disease characterised by hemolysis associated with the presence of immunoglobulins (IgG, IgM, or IgA) and/or components of complement system on red blood cells (RBCs), which is usually demonstrated by a positive direct antiglobulin test (DAT). Depending on the presence of an underlying disorder, AIHA can be subdivided into primary and secondary and, by the temperature at which autoantibodies bind optimally to RBCs, into warm antibody AIHA (wAIHA), mixed AIHA (including both warm IgG and cold IgM antibodies), cold agglutinin disease (CAD), Paroxysmal Cold Hemoglobinuria (PCH) and DAT negative AIHA. A frequent finding in immunohematology is the presence autoantibodies on RBCs without clinical symptoms of hemolysis that may later develop.

Izvorni jezik
Engleski

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