Pregled bibliografske jedinice broj: 1072397
Applicability of nanostructured lipid carriers for enhancing in vitro bioavailability of zeaxanthin
Applicability of nanostructured lipid carriers for enhancing in vitro bioavailability of zeaxanthin // Third All WGs UNGAP Meeting
Ljubljana, Slovenija, 2020. str. 2-3 (poster, međunarodna recenzija, sažetak, znanstveni)
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Naslov
Applicability of nanostructured lipid carriers
for
enhancing in vitro bioavailability of
zeaxanthin
Autori
Radić, Kristina ; Antunes Costa Lima, Sofia ; Vitali Čepo, Dubravka
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Third All WGs UNGAP Meeting
/ - , 2020, 2-3
Skup
Third All WGs UNGAP Meeting
Mjesto i datum
Ljubljana, Slovenija, 11.02.2020. - 12.02.2020
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Nanostructured lipid carriers, Zeaxanthin, bioavailability, CaCo-2/HT 29
Sažetak
Carotenoids are fat-soluble valuable phyto- nutrients that comprise a group of more than 700 compounds. Zeaxanthin (ZEA) belongs to the group of oxygenated derivatives of carotenoids called xanthophylls. Previous studies have shown the high antioxidant properties of natural ZEA. However, its low solubilization in physiological systems limit ZEA’s bioavailability. To enhance its absorptionin the gastrointestinal tract (GIT) we included lipids in delivery systems. When formulated as nanoparticles, that approach can result in improvement of mucosal adhesion of the molecule due to small particle size what can enhance GIT residence time. Between the formulations that contain lipids, we selected nanostructured lipid carriers( NLC) that are also able to protect the molecule from degradation.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
