Pregled bibliografske jedinice broj: 107100
Immunoregulatory properties of deciduas macrophages
Immunoregulatory properties of deciduas macrophages // 8th Congress of the Alps Adria Society for Immunology of Reproduction: abstracts, American Journal of Reproductive Immunology 48(3) / Rukavina, Daniel ; Gill, Thomas J. ; Clark, David A. (ur.).
Weimar, Njemačka: John Wiley & Sons, 2002. str. 142-142 doi:10.1034/j.1600-0897.2002.00024.x (pozvano predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 107100 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Immunoregulatory properties of deciduas macrophages
Autori
Sedlmayr, Peter ; Ćupurdija, Kristijan ; Azzola, Dagmar ; Dohr, Gottfried ; Wintersteiger, Reinhold ; Morales, Pedro ; Petrof, Margaret G. ; Hunt, Joan S. ; Gratchev, Alexei ; Goerdt, Sergij
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
8th Congress of the Alps Adria Society for Immunology of Reproduction: abstracts, American Journal of Reproductive Immunology 48(3)
/ Rukavina, Daniel ; Gill, Thomas J. ; Clark, David A. - : John Wiley & Sons, 2002, 142-142
Skup
8th Congress of the Alps Adria Society for Immunology of Reproduction
Mjesto i datum
Weimar, Njemačka, 07.09.2002. - 10.09.2002
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
immunoregulatory properties ; decidua macrophages
Sažetak
About 15-20 % of bone marrow derived cells in the endometrium and the decidua are CD14-positive macrophages coexpressing the scavenger receptor CD163. The costimulatory molecule CD86 (B7-2) but not CD80 (B7-1) is found expressed on first trimester and term decidua macrophages (D-Mph). The number of D-Mph increases at the implantation site in the basal decidua, where they are in contact with the HLA-Gpositive invading extravillous cytotrophoblast. As DMph express the inhibitory receptors CD85d (ILT4, LIR-2) and CD85e (ILT2, LIR-1), they are potentially susceptible to inhibition by class Ia and class Ib molecules. D-Mph may have specific functions relating to successful pregnancy, and phenotypic and functional properties may differ between early and term pregnancy. A number of data make their molecular repertoire comparable to those of alternatively activated macrophages which are immunosuppressive. For instance, first trimester decidua macrophages express IL-10 and the MS-1 high molecular weight antigen on the cell surface fibronectin and F XIIIa are detectable. Functional data are required to complement these studies.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE