Naslov
Gingival Papillomatosis as the Oral Sign of Cowden Syndrome: A Case Report

Autori
Glavina, Ana ; Bradamante, Mirna ; Glavina Durdov, Merica ; Mravak-Stipetić, Marinka

Izvornik
Acta Dermatovenerologica Croatica (1330-027X) 27 (2019), 4; 260-264

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Cowden syndrome ; gingival papillomatosis ; multiple hamartoma syndrome

Sažetak
Cowden syndrome (CS) is a rare autosomal dominant, hereditary, multiorgan disease with higher risk for malignancies (breast, thyroid, endometrium). Mucocutaneous lesions occur in 90% of cases and are characterized by facial trichilemmomas, oral mucosal papillomas, and benign acral keratoses. We present the case of a 39-year-old female patient with the chief complaint of “white spots” on the upper and lower attached gingiva accompanied with skin changes on the face, hands, and soles. The patient’s family medical history revealed that her mother had an endometrial polyp and the sister had thyroid cancer. In the patient’s medical personal history she reported follicular thyroid adenoma, thyroid abnormalities (i.e. lymphocytic thyroiditis), fibrocystic changes and juvenile breast papillomatosis, lipoma, multiple fibromas, and genitourinary tumors. Based on extensive family and personal medical history, physical examination and histopathological findings, diagnostic criteria were fulfilled for the diagnosis of Cowden syndrome.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina

POVEZANOST RADA