Naslov
Infiltrative Edema on FLAIR Images for Detection of CerebralGliomas
(ESNR 2016)

Autori
Kovacic, Slavica ; Ruzic Barsic, Antonija ; Miletic, Damir ; Rumboldt, Zoran

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
Neuroradiology / - : Springer Science+Business Media, 2016, 1-75

Skup
EUROPEAN SOCIETY OF NEURORADIOLOGY Diagnostic and Interventiona l39th ANNUAL MEETING 23rd Advanced Course in Diagnostic Neuroradiology 8th Advanced Course in Interventional Neuroradiology

Mjesto i datum
Beograd, Srbija, 15.09.2016. - 18.09.2016

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Infiltrative edema ; FLAIR ; Gliomas

Sažetak
Objectives: To asses the accuracy of fluid-attenuated inversion recovery(FLAIR) images in differentiation of cerebral mass lesions based on theextension of signal abnormality.Background: Two main types of cerebral edema are vasogenic and cyto-toxic. There is another type that resembles vasogenic edema but extendsinto the gray matter (cortical or deep), which has been called infiltrativeedema”. It has been proposed that this infiltrative edema may be specificfor gliomas.Methods: FLAIR images from the initial MRI (1.5 T scanner) of 81patients with definite diagnosis of intra-axial mass lesions (41 gliomas, 31 metastatic neoplasms, 4 abscesses, 3 tumefactive demyelinations, 2lymphomas) were retrospectively and independently evaluated by 2readers (neuroradiologists with 2 and 16 years of experience) for thepresence of infiltrative edema. The readers were blinded to all clinicalinformation and other MR sequences. Presence of infiltrative edema wasconsidered to be diagnostic for gliomas. Sensitivity and specificity weredetermined for each reader, and interrater agreement was estimated bykappa coefficient.Results: Reader A had sensitivity for gliomas of 53.7% (22/41), specific-ity was 72.5%. Reader B had sensitivity of 82.9% (34/41) and specificityof 75.0%. There was a moderate agreement between the readers: Kappa0.44 (95% CI 0.25-0.63).Conclusion: Our results suggest that differentiation of gliomas from othercerebral mass lesions based exclusively on distribution of perilesionalsignal abnormality on FLAIR images is not very reliable (sensitivity of83% or less) and only moderately reproducible.

Izvorni jezik
Engleski

POVEZANOST RADA