Naslov
The use of BMPs in children.

Autori
Antičević, Darko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Anstract Book of 6th International Conference on Bone Morphogenetic Proteins. / Vukičević, Slobodan ; Reddi, Harry - Zagreb : Hrvatsko društvo za kalcificirana tkiva, 2006, 113-113

Skup
6th International Conference on Bone Morphogenetic Proteins.

Mjesto i datum
Dubrovnik, Hrvatska, 11.10.2006. - 15.10.2006

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Bone morphogenetic protein ; children ; application

Sažetak
Numerous animal studies and clinical testing of rhBMP-7in humans have shown improvement in bone healing and repair in tibial non-unions and fresh fracture model. However, use of BMPs in children has not been considered in the past, because unknown influence on local growth plate and the possibility of unpredicted reactions in growing skeleton on occasion of tumor occurrence. Congenital pseudarthrosis of the tibia (CPT) is a rare and frustrating disease due to multiple unsuccessful surgeries and eventual amputation. Recently, a few papers reported on the application of rhBMPs-7 in children as adjuvant to standard treatment options. Controversies in clinical application of BMP in children are pointed out.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA