Naslov
Bronchial metacholine challenge in children

Autori
Ivković-Jureković, I ; Matijašić, N ; Navratil, M ; Topalušić, I ; Golmajer-Vlahović, I

Izvornik
Allergy : european journal of allergy and clinical immunology (0105-4538) 72 (2017), Suppl 103; 566-566

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
bronchial challenge ; metacholine ; children

Sažetak
Bronchial methacholine challenge is a non- specific provocation test performed to assess bronchial hyperresponsiveness {; ; BHR). Because of its direct action on the bronchial smooth muscle, no delayed reactions are observed. Methacholine induces a bronchospasm which is reversible after administration of bronchodilators and the challenge test is performed on an outpatient basis. The most common indication for methacholine challenge test (MCT) in children is suspected asthma. This test has high sensitivity and a high negative predictive value, but a lower positive predictive value. Thus, a positive MCT does not necessarily imply a diagnosis of asthma.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA