Naslov
Antiplatelet Therapy after Coronary Artery Bypass Graft Surgery, Inconsistency of Clinical Practice and Clinical Significance of Proven Resistance to Antiplatelet Agents

Autori
Sopek Merkas, Ivana ; Lakusic, Nenad ; Fuckar, Krunoslav ; Cerovec, Dusko ; Maric Besic, Kristina

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, pregledni

Knjiga
The Current Perspectives on Coronary Artery Bypass Grafting

Urednik/ci
Murashita, Takashi

Izdavač
IntechOpen

Grad
London : Delhi

Godina
2019

Raspon stranica

ISBN
978-1-83968-121-7

Ključne riječi
antiplatelet therapy, coronary artery bypass grafting (CABG), resistance to antiplatelet drugs, acute coronary syndrome (ACS), chronic coronary syndromes (CCS)

Sažetak
Antiplatelet therapy is a very important part of medical therapy for patients after acute coronary syndrome (ACS) as well as in a stable coronary artery disease (CAD). The use of antiplatelet therapy after coronary artery bypass graft surgery (CABG) still is a controversial theme in daily clinical practice. While guidelines referring to dual antiplatelet therapy (DAPT) after ACS with proceeding percutaneous coronary intervention (PCI) are uniform, there are doubts regarding DAPT after CABG, especially in setting of chronic coronary syndrome (CCS). Recommendations are mostly based on expert opinion and not on multiple randomized controlled trials (RCT) or meta- analyses. Resistance to aspirin (acetylsalicylic acid, ASA) or other antiplatelet drugs is known after CABG, and further RCTs are needed to assess the effect on clinical outcome as well as the role of DAPT after CABG.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

POVEZANOST RADA