Pregled bibliografske jedinice broj: 1057631
VITAMIN D DEFICIENCY AND INFLAMATION ACTIVITY IN CHRON'S DISEASE AT THE TIME OF DIAGNOSIS
VITAMIN D DEFICIENCY AND INFLAMATION ACTIVITY IN CHRON'S DISEASE AT THE TIME OF DIAGNOSIS // 5th International Congress on Controversies in Rheumatology and Autoimmunity (CORA 2019)
Firenza : München: Kenes Group, 2019. CORA19-0390, 1 (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 1057631 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
VITAMIN D DEFICIENCY AND INFLAMATION ACTIVITY IN
CHRON'S DISEASE AT THE TIME OF DIAGNOSIS
Autori
Rajkovaca I1, Miskic B2, Mihaljevic S3, Cosic V4, Vcev A4
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
5th International Congress on Controversies in Rheumatology and Autoimmunity (CORA 2019)
/ - Firenza : München : Kenes Group, 2019
Skup
5th International Congress on Controversies in Rheumatology and Autoimmunity (CORA 2019)
Mjesto i datum
Firenca, Italija, 14.03.2019. - 16.03.2019
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
vitamin D, deficiency, inflamation, bowel, chron, disease
Sažetak
Vitamin D deficiency is often found in patients with IBD. Vitamin D has immunomodulatory activity avoiding excessive immune response and has the function of repairing the intestinal mucosal barrier in IBD. Aims: determination level of vitamin D in patients with acute Chron's disease. Methods: We have analyzed 20 patients with Crohn`s disease at the time of diagnosis. We measured vitamin D levels, sedimentation rate, CRP and calprotectin levels at the time of diagnosis and compared them to CDAI score. Results: There was 12 male and 8 female patients, average age of 34.12 ±.6, 23. 60% of patients had vitamin D deficiency and 20% had vitamin D insufficiency. ( according The Institute of Medicine, USA). The mean CDAI was 286.12 ± 58.22. There was a negative correlation between CDAI and vitamin D deficiency (p= 0.63, p<0.05, Spearman rank correlation).Also we found correlation between calprotectin levels and vitamin D deficiency (p=0.50, p<0.05, Spearman rank correlation).Vitamin D levels are unrelated to sedimentation rate and CRP. Conclusions: Our study confirmed previous results about vitamin D deficiency and insufficiency being prevelent in IBD. Also, vitamin D defficiency is associated with higher calprotectin levels and CDAI suggesting its potential antiinflammatory role in intestinal tissue.
Izvorni jezik
Engleski
Znanstvena područja
Interdisciplinarne tehničke znanosti, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)
POVEZANOST RADA
