Naslov
Usporedba metoda zelene kemije u sintezi Schiffovih baza na bazi kinazolinona
(A comparison of green chemistry methods in synthesis of quinazolinone based Schiff bases)

Autori
Komar, Mario ; Prašnikar, Fran ; Molnar, Maja

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts XIII Meeting of Young Chemical Engineers / Dejanović, Igor ; Vrsaljko, Domagoj ; Žižek, Krunoslav - Zagreb : Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI), 2020, 164-164

ISBN
978-953-6894-71-0

Skup
XIII. susret mladih kemijskih inženjera (SMLKI 2020)

Mjesto i datum
Zagreb, Hrvatska, 20.02.2020. - 21.02.2020

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
kinazolinon, Schiffove baze, zelena kemija, mikrovalovi, ultrazvuk, mehanosinteza
(quinazolinone, Schiff bases, green chemistry, microwaves, ultrasound, mechanosynthesis)

Sažetak
In the recent years, to avoid or minimize the damage of environment, ultrasound-assisted synthesis (UAS), microwave-assisted synthesis (MAS) and mechanochemical synthesis (MS) are important modern green techniques for synthesis of organic compounds. The quinazolinone core and its derivatives have been studied because of their wide range of biological activites such as antibacterial, antifungal, antitumor, anticolvulsant, antiinflammatory and antimicrobial. The main goal of this study was to investigate the yields and time required for the completion of reaction for Schiff bases. A series of quinazolinone based Schiff bases were synthesized via condensation of 3-amino-2-methyl- 4(3H)quinazolinone with substituted benzaldehydes by microwave, ultrasound and mechanochemical mixing. The novel procedure features short reaction time, moderate yields and simple workup.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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