Pregled bibliografske jedinice broj: 1056852
Investigation of sublethal effects of four commonly used pesticides on zebrafish larvae
Investigation of sublethal effects of four commonly used pesticides on zebrafish larvae // YES 2020 Meeting Program and Abstract Book
Waco (TX), Sjedinjene Američke Države, 2020. str. 37-37 (poster, međunarodna recenzija, sažetak, znanstveni)
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Naslov
Investigation of sublethal effects of four
commonly used pesticides on zebrafish larvae
Autori
Lackmann, Carina ; Velki, Mirna ; Seiler, Thomas- Benjamin ; Hollert, Henner
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
YES 2020 Meeting Program and Abstract Book
/ - , 2020, 37-37
Skup
9th SETAC Young Environmental Scientists Meeting
Mjesto i datum
Waco (TX), Sjedinjene Američke Države, 09.03.2020. - 11.03.2020
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
pesticides ; zebrafish ; fluorescence ; oxidative stress ; MXR
Sažetak
In recent years the debate about the usage of pesticides has increased widely. Biodiversity has not only been in observed in Germany but worldwide and is often linked to side-effects of pesticide usage. A vast biodiversity decline is not only a concern for entire ecosystems and food chains but could indirectly also impact ecosystem services. Due to e.g. rainfall pesticides can end up in aquatic systems and thus potentially cause negative effects on non- target organism. Improving the investigative tools for the assessment of pesticide effects is therefore necessary, to be able to understand their modes of action in more detail and extend the available data for pesticides already in use. An increased assessment often calls for a higher usage of test organisms, resulting in a dilemma as it has been an important aim to minimize the usage of laboratory animals. In this study, the effects of four pesticides on zebrafish larvae (Danio rerio) are assessed: namely, insecticides thiacloprid, esfenvalerate and herbicides prosulfocarb and dimethenamid-p. As current regulations only include standardized toxicity testing of the active substances, important data is missing on the different modes of action and possibly varying toxicity of commercial formulations and therefore both are investigated in this study. A comprehensive test-battery has been used and a workflow established to assess multiple sublethal endpoints, e.g. fluorescence-based methods oxidative stress and MXR activity detection as well as behavioral changes and biomarker measurements with a minimal number of test organisms.
Izvorni jezik
Engleski
Znanstvena područja
Biologija