Naslov
Salivary level of IL-2 in patents with denture stomatitis before and after low-level laser therapy

Autori
Uhač, Mia ; Pezelj-Ribarić, Sonja ; Šimunović- Šoškić, Marica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
2nd International Dental Students Congress (RiCON) abstract book / - , 2017, 20-20

Skup
RiCON - 2. International Dental Students Congress

Mjesto i datum
Rijeka, Hrvatska, 31.03.2017. - 02.04.2017

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Denture stomatitis ; Inteleukin-2 ; Low-level laser therapy

Sažetak
Introduction: The denture stomatitis (DS) is a common oral mucosal lesion that occurs in denture wearers. A low-level laser treatment (LLLT) is a potential noninvasive treatment for DS due to its anti- inflammatory and biostimulation effects. Objective. The objective of this study was to monitor therapeutic response to LLLT by measuring thesalivary level ofproinflammatory cytokineinterleukin-2 (IL-2) in patients with DS. Materials and Methods. The study included20 subjects with DS (Newton type II DS) and 20 healthy volunteers. The clinical examination was performed according to the standard clinical criteria. DS patients were placed on therapy with LLLT for four consecutive weeks. A whole unstimulated saliva were colected before and after LLLT. For determination of salivary level of IL-2 ELISA (Sigma Immunochemicals, St Louis MO, USA) test was performed. Results: In the experimental group, levels of IL-2 measured before LLLT were significantly greater (0.459 ± 0.127) than IL-2 levels following therapy (0.246 ± 0.058) (p < 0.001). In the control group, no significant difference was found in the levels of IL-2 before (0.203 ± 0.090) and after (0.201 ± 0.067) the application of LLLT(all p values >0.05). Following treatment with LLLT for 4 weeks the levels IL-2 decreased significantly and the levels of this pro- inflammatory cytokine was significantly different from controls. Conclusion: This study showed that LLLT may be an efficacious choice for DS therapy.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Dentalna medicina

POVEZANOST RADA