Naslov
Characteristics of microbiologic profile in cervical samples of pregnant women and nonpregnant healthy young women

Autori
Kaliterna, Vanja ; Kučišec-Tepeš, Nastja ; Pejković, Lidija ; Borzić, Elmica ; Barišić, Zvonimir ; Zoranić, Vinko ; Jeličić, Ivana.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Clinical Microbiology and Infecton, 14th European Congress of Clinical Microbiology and Infection / - Prag : ESCMID, 2004, 471-471

Skup
14th European Congress of Clinical Microbiology and Infection

Mjesto i datum
Prag, Češka Republika, 01.05.2004. - 04.05.2004

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
cervix ; pregnant women

Sažetak
Objectives: This study compares frequency of the most common isolates of genital tract between two groups: pregnant women (in first and third trimester of pregnancy) and nonpregnant healthy young women. Our goal was to define how many of them have colpitis in compare with them who have only colonisation. Methods: Collected samples, endocervical swabs, were treated according to the standard laboratory procedures. Methods included: direct smear for inflammatory cells, dominant growth of etiologic bacterial agent after standard cultivation, biotyping, determination of antibiotic susceptibility and mycologic identification. Results: During the 1-year period of investigation 95 pregnant women (each one in first and third trimester of pregnancy) and 102 nonpregnant healthy young women were controlled. All women were in generative age (20–43 years old). The patients with inflammatory cells (>10 per field), clinical symptoms and isolate were considered to have colpitis. The cases with microbiological isolate, epithelial cells in direct smear were considered as colonisation. The most common isolates in pregnant women in first trimester were: S. agalactiae (14%), E. coli (11.5%), Candida (15.4%), while in third trimester the most common isolates were: Candida (32%), E. coli (7.6%) and S. agalactiae (6.4%). The isolates of nonpregnant healthy women included: S. agalactiae (8.8%), E. coli (8.8%) and Candida (16.6%). We noticed that women with isolated S. agalactiae or E. coli had deficit of Lactobacillus (only 11–13%) in comparison with women without pathogens (50–54%) in both groups. Inflammatory cells were found in 12.7% direct smears of nonpregnant women and in 5% of pregnant women. Conclusion: In this study the most common isolates were S. agalactiae in first trimester of pregnancy. Candida was the most frequent in third trimester, which is in connection with elevate of pH in late pregnancy (but only 21.6% of them had conidial forms in direct smears which can be considered as infection). Lactobacillus concentracion is severely depressed in women with some other isolates wich can be explained as run for free areas. Amount of inflammatory cells is significantly elevated in nonpregnant women. Such a finding could be both the result of better control in pregnancy and the fact that pregnant women usually have only one partner. A complete evaluation of the cervical swabs in pregnancy should be preventive strategy for useful informations to obstetricians in order to avoid neonatal diseases.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA