Naslov
Extremely low birth weight infant, late morbidities and health outcomes

Autori
Papazovska Cherepnalkovski, Anet ; Bucat, Marija ; Furlan, Ivanka ; Pavlov, Vesna ; Družić, Mila ; Budimir, Majda ; Brajkovic, Luka

Izvornik
Paediatria Croatica (1330-1403) 62 (Supl 1) (2018); 22-27

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
extremely low birth weight infants ; late morbidities ; follow up ; University Hospital of Split

Sažetak
Extremely low birth weight infants (ELBW) are those of birth weight of less than 1000 g and are usually born at ≤27 weeks’ gestation. We identified several major contributors to late morbidity in this group, namely bronchopulmonary dysplasia (BPD), late- onset infections, necrotizing enterocolitis, central nervous system manifestations, retinopathy (ROP) and anemia of prematurity. We estimated incidence and severity for each of these manifestations among our 41 study subjects of ELBW. We found low incidence of BPD- 7%. Severe ROP requiring laser photocoagulation and/or bevcizumab treatment was observed in 17.1% patients. Intraventricular hemorrhage (any grade) was noted in 11 (29%) of the patients. Diffuse cystic periventricular leucomalacia was present in only 1 patient (2.4%) of the deceased group. We showed high incidence of late-onset infection (73%), most frequent pathogens were Meticilin Resistant Staphylococus Epidermidis and Acinetobacter baumanii. Candida was infrequently present in hemoculture due to the strict policy of prophylaxis with fluconazole. No cases of hydrocephalus or necrotizing enterocolitis were described. A larger study group is needed to draw conclusions on morbidities’ incidences and association with departments’ treatment strategies. We concluded that, specific follow up goals should be set for these ELBW infants upon discharge, most importantly for early identification of developmental disabilities and identification and treatment of medical complications. Close cooperation is required between neonatologists and the subspecialties further involved in follow up of these children.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA